Francesco di Crescenzo was born in Pordenone on 9 September 1991. Since he was a child he has cultivated his passion for acting, going from children's entertainment to theater workshops in high school.
He graduated in 2010 at the Liceo Scientifico “E. Torricelli" in Maniago, then he graduated in "Multimedia Sciences and Technologies" in 2013. During his university years he took part as an actor in the creation of a web series on the functioning of the university library, "Stories from the library". In 2014 he enrolled in the "Scuola Popolare di Teatro" in Pordenone and, a few weeks after enrolment, he was chosen as the leading actor in a show written and directed by the director of the school, Bruna Braidotti, entitled "Between two fires".
In 2016 he was among the protagonists of the Web Series “A.M.I. – Android for Medical Innovation”, winner of the Janssen “Hi Future!” special prize at the Roma Web Fest. In June 2019 he graduated with honors from the prestigious International Academy of Theater in Rome. In 2022 he made his cinema debut with a small role in the film "Quasi orfano".